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(Research ongoing) Professor Yan Bing: Advances in Research on Rare Earth-MOFs Nanofluorescence Probes
Published:2017-03-01 Hits:424

 

With the development of modern industry, a large number of toxic and hazardous substances enter into the environment, water, atmosphere and food residues, posing a long-term threat to human health. Therefore, the establishment of rapid detection technology in environmental pollutants has a crucial role for environmental pollution prevention and control, protection of human health and ecological environment. Combined with rare earth ions and the structural properties of metal organic frameworks (MOFs), rare earth luminescence MOFs are widely used as fluorescent probes for the detection of environmental pollutants due to their excellent luminescent properties.

However, environmental monitoring does not reflect the total amount of harmful substances that are exposed to different routes (air tube, alimentary canal and skin), and the level of hazardous substances in the environment does not equal the actual exposure and absorption of the human body. Besides, environmental monitoring cannot effectively reflect individual differences and the resulting differences in absorption. As an effective supplement to environmental monitoring, biological monitoring can provide the internal dose of harmful substances in the human body, which can reveal the connotation of pollutants and human health, so it is of great practical value in environmental health risk assessment.

Professor Yan Bing has been engaged in research work in photofunctional lanthanide hybrid materials and metallic oxides and oxy salts, and focused on Construction, optical integration, and luminescent sensing properties of lanthanide hybrid materials based on crystalline matrix. (Chem. Commun. 2014, 50, 9969-9972、13323-13326、15235-15238、15443-15446; 2015, 51, 7737-7740、14509-14512; 2016, 52, 2265-2268. J. Mater Chem. A 2014, 2, 13691-13697、18018-18025; 2015, 3, 4788-4792; 2017, 5, 2215-2223. J. Mater. Chem. C 2014, 2, 5098-5104、5526-5532、6758-6764、7411-7416; 2015, 3, 2823-2830、7038-7044、8413-8418、9353-9358; 2016, 4, 1543-1549、8514-8521. Nanaoscale, 2015, 7, 4063-4069; 2016, 8, 2881-28861、2047-12053. Inorg. Chem. 2014, 53, 3456-346; 2016, 55, 11831-11838 etc.) Recently, they tried to use Ln-MOFs as a fluorescent probe for the detection of biomarkers of organic compounds such as toluene and polycyclic aromatic hydrocarbons (PAHs) in urine, and achieved efficient biological monitoring in these harmful substances. The related research results were published in the International Journal of Advanced Materials (Adv. Funct. Mater), entitled "Determination of Urinary 1-Hydroxypyrene for Biomonitoring of Human Exposure to Polycyclic Aromatic Hydrocarbons Carcinogens by a Lanthanide-functionalized Metal-Organic Framework Sensor" . 2017, 27, 1603856, Journal Impact Factor 11.382). The first author is Hao Jina. She has won two doctoral scholarships, with eight representative papers with more than 60 factors.

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